Functional Organic Materials Laboratory Department of Chemistry, Graduate School of Science, Nagoya University
Institute of Transformative Bio-Molecules


Prof. Dr. Shigehiro Yamaguchi

Phone: +81-52-789-2291

Shigehiro Yamaguchi graduated from Kyoto University in 1991 and received his Dr. Eng. from Kyoto University in 1997. He worked with Professor Kohei Tamao at the Institute for Chemical Research, Kyoto University as an Assistant Professor from 1993. He also spent a year to work with Professor Timony M. Swager in Massachusetts Institute of Technology, USA as a visiting scholar from 2000 to 2001. He joined Nagoya University as an Associate Professor in 2003, and promoted to a full Professor in 2005. Prof. Yamaguchi's research interests include the materials chemistry on the basis of main group chemistry. Making use of specific effects of main group elements, particularly boron, silicon and phosphorus, he has so far produced a range of molecules with both fascinating structures and properties, which can serve numerous purposes, such as anion sensors, light emitters, and electron-transporting materials. He is also currently engaged in a project that aims at the development of fluorescence probes for bioimaging. His contributions have been recognized with a number of research awards, such as the JSPS Award (2013), the Mukaiyama Award (2015), the Chemical Society of Japan Award for Creative Work (2016), Merck-Karl Pfister Visiting Professor in Organic Chemistry, MIT (2017), Humboldt Research Award (2019), and Russel Lecture, Queen's University.


  • Chisso Award in Synthetic Organic Chemistry, Japan (1997)
  • Young Scientist Award of the Silicon Chemical Society of Japan (1999)
  • The Chemical Society of Japan Award for Distinguished Young Chemists (2002)
  • Young Scientist Award from the Minister of Education, Culture, Sports, Science and Technology (2005)
  • Tokyo Techno Forum 21 Gold Medal (2007)
  • Nozoe Award for Young Scientist (2008)
  • NISTEP Nice Step Researcher (2008)
  • DIC Award from Synthetic Organic Chemistry, Japan (2009)
  • JSPS Award (2013), Mukaiyama Award (2015)
  • CSJ Award for Creative Research (2016)
  • Nagase Foundation Award (2016)
  • Merck-Karl Pfister Visiting Professor in Organic Chemistry, MIT (2017), Ichimura Academic Award (2018), Humboldt Research Award (2019), Russel Lecture, Queen’s University (2019)

Other Contributions

  • Org. Lett., Associate Editor (2013-)
  • Chem. Soc. Rev., International Advisory Board (2014-)
  • J. Org. Chem., International Advisory Board (2016-)

Representative publications

  1. A Photostable Fluorescent Marker for the Super-Resolution Live Iimaging of theDynamic Structure of the Mitochondrial Cristae
    C. Wang, M. Taki, Y. Sato, Y. Tamura, H. Yaginuma, Y. Okada, and S.Yamaguchi
    Proc. Natl. Acad. Sci. USA, in press (2019).
  2. Near Infrared Two-Photon-Excited and -Emissive Dyes Based on a Strapped Excited-State Intramolecular Proton-Transfer (ESIPT) Scaffold
    N. Suzuki, K. Suda, D. Yokogawa, H. Kitoh-Nishioka, S. Irle, A. Ando, L. M. G. Abegão, K. Kamada, A. Fukazawa, S. Yamaguchi
    Chem. Sci., 9, 2666-2673 (2018).
  3. A Highly Photostable Near-infrared Labeling Agent Based on a Phospha-rhodamine for Long-term and Deep Imaging
    M. Grzybowski, M. Taki, K. Senda, Y. Sato, T. Ariyoshi, Y. Okada, R. Kawakami, T. Imamura, S. Yamaguchi
    Angew. Chem. Int. Ed., 57, 10137-10141 (2018).
  4. Seeded Polymerization through the Interplay of Folding and Aggregation of an Amino-Acid-based Diamide
    S. Ogi, K. Matsumoto, S. Yamaguchi
    Angew. Chem. Int. Ed., 57, 2339-2343 (2018).
  5. Boron-Stabilized Planar Neutral π-Radicals with Well-Balanced Ambipolar Charge-Transport Properties
    T. Kushida, S. Shirai, N. Ando, T. Okamoto, H. Ishii, H. Matsui, M. Yamagishi, T. Uemura, J. Tsurumi, S. Watanabe, J. Takeya, S. Yamaguchi
    J. Am. Chem. Soc., 139, 14336-14339 (2017).